The Venture Bros.

Doc Hammer

Dr. Girlfriend / Henchman 21 (voice)

Christopher McCulloch

Hank Venture / The Monarch (voice)

Patrick Warburton

Brock Samson (voice)

James Urbaniak

Dr. Venture (voice)

Michael Sinterniklaas

Dean Venture (voice)

Lisa Hammer

Triana Orpheus (voice)

Steven Rattazzi

Dr. Orpheus (voice)

Paul Boocock

Dr. Jonas Venture (voice) / Dr. Jonas Venture / Additional Voices (voice) / Dr. Jonas Venture / More Pirates (voice) / Dr. Jonas Venture / OCLF Leader (voice) / Fighter Pilot / O.S.I. Instructor (voice) / Highway Cop / Scared Straight Kid 1 (voice) / Jona

Cristin Milioti

Kate (voice) / Madison (voice) / Millinery Ghosts (voice) / Mrs. Fitzcarraldo (voice) / Mrs. Wandering Spider (voice) / Night Nurse Cindy Marie Abrams (voice) / Nurse (voice) / Receptionist / Sirena (voice)

Brendon Small

Action Johnny (voice) / Agent Hauser (voice) / Jonny Quest (voice) / Plastic Surgeon (voice) / Resistance 1 (voice) / Sgt. Hatred (voice) / Surgeon / OSI Scientist / SPHINX Agent 1 (voice) / Swifty / Hector / Crime-o-dile Henchman / White Noise (voice)

Bill Hader

Professor Impossible (voice) / Professor Impossible / Alien villain (voice) / Professor Impossible / Phage (voice)

Dana Snyder

President Breyer (voice) / The Alchemist (voice)

Toby Huss

General Treister (voice) / Scaramantula (voice)

H. Jon Benjamin

The Master (voice)

Stephen Colbert

Professor Impossible (voice)

Charles Parnell

Jefferson Twilight (voice) / Mandalay (voice)

Kevin Conroy

Captain Sunshine (voice)

Misha Collins

Prisoner 2 / Maestro Wave (voice)

Patton Oswalt

Wonderboy (voice)

Nathan Fillion

Brown Widow (voice)

Seth Green

Lance Hale / Mrs. Z (voice)

Steve Park

Mike Sorayama (voice)

John Hodgman

Dale Hale (voice)

Gillian Jacobs

Marsha Backwood (voice)