Bill Nye sauve le monde

Bill Nye

Himself - Host

Derek Muller

Himself - Correspondent

Prashanth Venkataramanujam

Casting Director / Cookies & Cream (voice) / Himself

Karlie Kloss

Herself - Correspondent

Rachel Bloom

Herself - Special Guest / Martian

Cece Pleasants

HPV / Voice of Wilhelmina

Sanden Totten

Ebola / Voice of Refrigerator

Nazeem Hussain

Himself - Correspondent

Joanna Hausmann

Herself - Correspondent

Emily Calandrelli

Herself - Correspondent

Mark Jacobson

Himself - Panelist

Zach Braff

Himself

Desiigner

Himself

Tracy Mann

Herself - Panelist

Sara Benincasa

Herself - Panelist

Jennifer Widerstrom

Herself - Panelist

Martin Starr

Doug the Caveman

Lauren Ash

Kale

Jeff Dye

Eggplant

Andi Osho

Bread

Heather McDonald

Beef

Aubrey Anderson-Emmons

The Director

Robb Fraley

Himself - Panelist

Fred Gould

Himself - Panelist

Julie Kennye

Herself - Panelist

Katrina Karkazis

Herself - Panelist

Jeffrey McCune Jr.

Himself - Panelist

Solomon Georgio

Himself - Panelist

Todd Barry

Vanilla (voice)

Sandra Bernhard

Mint Choc Chip (voice)

Matt Lucas

Salted Caramel (voice)

Mario Cantone

Strawberry (voice)

Margaret Cho

Pistachio (voice)

Cameron Esposito

Chocolate (voice)

Nicole Go

DJ Seahorse

Ryan Calo

Himself - Panelist

Xeji Jardin

Herself - Panelist

Subbarao Kambhampati

Himself - Panelist

Neil deGrasse Tyson

Voice of Coffee Maker

Salim Shaikh

Himself

Margaret Mitchell

Herself

Prof. Mark Jacobson

Himself - Panelist

Richard Martin

Himself - Panelist

Taryn O'Neill

Herself - Panelist

Steve Aoki

Himself

Chris Beedie

Himself - Panelist

Cara Santa Maria

Herself - Panelist

Donald Schultz

Himself - Panelist

Alton Brown

Himself

Hunter Pence

Himself

Randy Couture

Tardigrade

Marcus Lindsay

Tardigrade Victim

Andy Rossi

Tardigrade Victim

Moogega Cooper

Herself - Panelist

Hakeem Muata Oluseyi

Himself - Panelist

Wil Wheaton

Himself - Panelist

Lanre Falusi

Herself - Panelist

Kristen Omeara

Herself - Panelist

Jennifer Reich

Herself - Panelist

Diedrich Bader

Smallpox

Jim O'Heir

Rabies

John O'Hurley

Influenza

George Wendt

Polio

Hilarie Cash

Herself - Panelist

Shawn Green

Himself - Panelist

Jonna Mae

Herself - Panelist

Gustavo Sorola

Rooster Teeth

Geoff Ramsey

Rooster Teeth

Tim Gunn

Himself

Camille Hammond

Herself - Panelist

Leslie Hinkson

Herself - Panelist

Paul Knoepfler

Himself - Panelist

Nerys Benfield

Herself - Panelist

Travis Rieder

Himself - Panelist

Rachel Snow

Herself - Panelist