La saison 5 de Roadkill a été diffusée sur MotorTrendOnDemand du vendredi 19 février 2016 au dimanche 25 décembre 2016. Elle comporte 13 épisodes, le premier s'intitule "Wrecker Adventure! Harry Tow Meets Pigpen" et le dernier "Roadkill vs. Mighty Car Mods!".
Ride along with HOT ROD's David Freiburger and Mike Finnegan as they continue their love/hate relationship with hot rods, street machines and other highly strung performance vehicles. In Roadkill, Freiburger and Finnegan hit the road in everything from a 1968 Ford Ranchero to a 1500 horsepower Camaro called the F-Bomb. Just getting to their destination is an adventure.