NOVA

John Prasher

Joey as a Young Man

Carl Sagan

Self

Duncan Carse

Narrator

Bernard Arcand

Self

Dr. John E. Mack

Self - Psychiatry, Harvard Medical School

George Pataki

Self

Heather Berlin

Self

James R. Schlesinger

Self (archive footage)

William H. Whyte

Self

Manfred von Richthofen

Self (archive footage)

R. Allen Gardner

Self

Sue Savage-Rumbaugh

Self

Patricia Marks Greenfield

Self

Christopher Molesworth

Joey as a Boy

Antonio Regalado

Self

Rodolphe Barrangou

Self

Jennifer Doudna

Self

George Church

Self

David Baltimore

Self

Robert Sinsheimer

Self

Sarah Boyson

Self

Duane Rumbaugh

Self

Reinhard Genzel

Self

Robert Michelson

Self

Laurence Golborne

Self

Héctor Elizondo

Narrator

Susan Sarandon

Narrator (voice)

Derek Jacobi

Voice of Ernest Shackleton

William Hootkins

Voice of Methuselah

Roger McGough

Narrator

Vladimir Pozner

Host

Rena Baskin

Narrator

Sigourney Weaver

Narrator

Cornelius Garrett

Voices of the Ambassador and Castelli

Robert Krulwich

Correspondent

Hal Linden

Narrator

John Hurt

Narrator

Zachary Quinto

Narrator

John Hawks

Himself

Zeresenay Alemseged

Himself

Lee Rogers Berger

Himself

Richard Allinson

Narrator

Jan Maxwell

Narrator

Jeremy Akerman

Parslow

Sally Kellerman

Narrator

Rebecca De Mornay

Narrator

Alexa Jago

Voice of Maria Celeste

Joseph Deacon

Joey Today

Martin K.A. Morgan

Self

David Suzuki

Narrator (voice)

Robin King

Narrator (voice)

Alexander John

Narrator (voice)

Joseph Campanella

Narrator (voice)

Ray Moore

Narrator (voice)

Linus Pauling

Self

Jeremy Keenan

Anthropologist

Frank Gillard

Narrator (voice)

Eve Karpf

Woman

Harry Mannis

Narrator (voice)

Will Lyman

Narrator (voice)

Bill Mason

Narrator (voice)

Homer H. Hickam Jr.

Self

Robert D. Ballard

Self

Natalie Rose

Josephine Baker

Mimi Michaela Konoza

High School Student (uncredited)

Stephen Jay Gould

Self

Lanie Zera

Narrator (voice)

Ursula Drabik

Narrator (voice)

Richard Kiley

Narrator (voice)

Lee Grant

Narrator (voice)

Brian Poyser

Shudenko

David James

Gorshkov

Michael David

Agrobiologist

Greg Moore

Self

Paul Erdös

Self

Jean Dieudonne

Self

Gregory Harris

J.E. Littlewood (voice)

A. Tarcisius

Indian Voices (voice)

Shankara Murthi

S. Ramanujan (voice)

Mark Wing-Davey

Joey's Father

Anita Carey

Joey's Mother

Ernie Roberts

Ernie Today

Maureen Stapleton

Narrator (voice)

David Rose

Self

Richard Post

Self

Noel Davis

Scientist

Richard Beale

Lysenko's Father

Forbes Collins

Iakovlev

George Cormack

Ivan Michurin

Richard Ireson

Prezent

Simon Lack

Zhukovsky

David Swift

Nikolai Vavilov

Terrence Hardiman

Trofim Lysenko

William Franklyn

Narrator (voice)

Tony Robinson

Younger Ernie

Shu Morino

Reporter

Christian Pedersen

Gustav Wiik / Otto Hahn

Stockard Channing

Narrator (voice) / Self - Bible Reader

Salvatore Vecchio

Narrator

John Mckenzie

Narrator

Valerie Harper

Narrator (voice) / Self

Kirk Johnson

Host

John Hockenberry

Narrator

Roy Scheider

Narrator

Joe Morton

Additional Narration / Narrator

Kathryn Walker

Narrator

Oliver Platt

Narrator

Edd Gasper

Narrator

Kenichi Nakamaru

Reporter

Jim Carter

Narrator

Michael Scott

Narrator

Bray Poor

Narrator

Courtney B. Vance

Narrator

Don Wescott

Narrator (voice)

Martin Jarvis

G.H. Hardy (voice) / Narrator (voice)

Beatrix Gardner

Self

Ian Holm

Narrator / Narrator (voice)

Tony Kahn

Narrator

David Attenborough

Narrator

Talithia Williams

Self - Narrator

Corey Johnson

Narrator

David Ogden Stiers

Narrator

Stacy Keach

Narrator / Narrator (voice)

Will Lyman

Narrator / Narrator (voice)

Liev Schreiber

Narrator (voice)

Neil Ross

Narrator

David Pogue

Host

Craig Sechler

Narrator / Self - Narrator

Lance Lewman

Narrator (voice)

John Lithgow

Narrator

Brian Greene

Host

Neil deGrasse Tyson

Self - Host / Self - Narrator

Paul Vaughan

Narrator / Narrator (voice)

Richard Smith

Host

Ted Marcoux

Narrator

Demetri Goritsas

Narrator

Jeremiah Kissel

Narrator

Gene Galusha

Narrator

Richard Donat

Narrator

Peter Thomas

Narrator

Jamie Effros

Narrator

Jay O. Sanders

Narrator / Narrator (voice)

Eric Meyers

Narrator

John Fraser

Inquisitor

Maureen Bennett

Lady Franklin

Anthony Garner

Sir John Franklin

Scott Handy

Isaac Newton

F. Murray Abraham

Narrator

James Tovell

Manson

Di Trevis

Baroness de la Garde

Philip Herbert

Count de Amerval

Robert Styles

Newman

Samuel West

Humphry Davy

Thom Fell

James Fitzjames

Bohdan Poraj

Francis Crozier

Corey Conradi

Roald Amundsen

Laura Nardi

Maria Celeste

Simon Callow

Galileo

C. Scott Willis

Reporter

Calvin Sims

Reporter

Natalie Rose

Josephine Baker

Keith David

Narrator

Jere Shea

George Soper

Marian Tomas Griffin

Mary Mallon

Darri Ingolfsson

Godfred Hansen

Alex Macqueen

Chater

Emily Woof

Lise Meitner

Anton Lesser

Voltaire

David Slavin

Narrator

Rob Tinworth

Narrator

Alan Yentob

Narrator

John Benjamin Hickey

Narrator

Stefanie E. Frame

Narrator

Mark Oliver Everett

Himself

Rushmore DeNooyer

Narrator

Nigel Bennett

Sir Charles Lyell

Frances O'Connor

Emma Darwin

Ray Magliozzi

Host

Tom Magliozzi

Host

Harrison Ford

Narrator

Stephen Noonan

Marat

Brendan Fleming

Hermann Einstein

Ty Glaser

Marie Anne Lavoisier

Julian Rhind-Tutt

Antoine Lavoisier

Steven Robertson

Michael Faraday

Shirley Henderson

Mileva Maric

Aidan McArdle

Albert Einstein

Ruben Santiago-Hudson

Percy Julian

E.O. Wilson

Himself

Henry Ian Cusick

Charles Darwin