Their new opponent is big, red and more powerful than ever: Now Joko and Klaas are not competing against each other for the first time, but instead challenge an entire broadcaster. In the new prime time show series "Joko & Klaas against ProSieben", the goal is to compete against the entire universe of the red seven. Moderators, editors, entire programs - Joko and Klaas invite everyone to the cross-program strength test in various game rounds. Their opponents and the associated tasks are set up by ProSieben, the broadcaster alone decides about the opponents of Joko and Klaas and the games. After the show, the billing is done: if the two show masters triumph over their employer, the broadcaster gives them a 15-minute live slot in the program for unrestricted composition. If ProSieben emerges victorious from the evening, Joko and Klaas must unconditionally put themselves at the service of their broadcaster.