Set at the offices of AiRBLUE, a rookie voice acting agency with no track record or experience, CUE! follows the trials and tribulations of a group of young women who follow their dreams of becoming voice actors. But the voice acting world is highly competitive, and no matter how much someone practices, not everyone will make it past the audition process. Despite frustrations and setbacks, the story of a new generation of voice actors is about to begin.