Newly qualified midwife Jenny Lee arrives in the East End to embark on a challenging career alongside an order of nursing nuns.
As Jenny Lee settles into her role, there is a new arrival at Nonnatus House, Chummy.
Jenny is placed on the nursing roster to extend her experience of community practice.
When a baby is snatched from her pram, the local community unites to search for the child.
Jenny provides care for cancer patient Frank, and learns that love can come in many forms.
Jenny learns midwifery is full of surprises when Sister Monica Joan is put on trial.
When an abandoned baby is discovered on the steps of the convent, the whole community comes together to provide food and try to find his mother.
It's 1958 and the day after celebrating her birthday, Nurse Jenny Lee is assigned a patient who is trapped in an abusive marriage.
While Chummy prepares for mission work in Sierra Leone, Cynthia loses faith in her abilities, and Jimmy walks back into Jenny's life.
Jenny is sent to a short-staffed London hospital. Back at Nonnatus House, the nuns and midwives meet a pair of twins, one of whom is pregnant.
Returning from her stint at The London Hospital, Jenny and Sister Evangelina assist at the birth of the Roberts' baby, who is born with spina bifida.
The community pulls together to prepare for the annual Summer Fete and with the addition of a Baby Show, the midwives will be more involved than ever.
With the advent of the mass-Xray program, Dr Turner is determined that the community will no longer live under the threat of Tuberculosis.
Cynthia finds herself administering daily insulin injections to diabetic John Lacey, a man who consistently belittles his wife Annie.
Chummy and PC Noakes settle back down to life in Poplar and Jenny's own jubilation comes in the form of potential love interest Alec.
The residents of Poplar prepare for Christmas, but an unexploded bomb is discovered, throwing festivities into chaos.
Sister Monica Joan holds the key to the diagnosis of a mystery illness.
Trixie's feathers are ruffled when Jenny is promoted to "Acting Sister" by Sister Julienne.
Shelagh suffers devastating news and the midwives help pregnant inmates at Holloway Prison.
Jenny rushes to Alec's side when he is taken to the hospital after a horrific accident.
When a woman with Down's syndrome discovers she is pregnant, she faces a hard decision.
Patsy struggles to adapt to the unpredictable and chaotic working life of midwifery.
Sister Julienne must talk new mother Pamela down when she is found on the edge of a pier.
Shelagh and Dr. Turner nervously await life-changing news from the Adoption Society.
A present-day Jennifer recalls her youth at Nonnatus House; Chummy and Patsy bring joy to the festivities; Cynthia makes a life-changing decision.
An encounter with a needy child forces Trixie to see a darker side of life; Nonnatus House welcomes a new nurse; Tom plans a romantic surprise.
A problematic birth causes Barbara to doubt herself; a man from Sister Julienne's past returns; the new nurse fails to impress Sister Evangelina.
Poplar suffers a mysterious outbreak of dysentery; an expectant couple's life is turned upside down when the husband is arrested for moral indecency.
The midwives are in for a busy night when Sister Winifred focuses her efforts on Poplar's prostitutes. Cracks appear in Trixie and Tom's relationship.
Sister Julienne's faith is tested when a mother refuses medicine for her newborn. Dr. Turner's role in the case forces him to face his own demons.
A diabetic teen faces heartbreak when she falls pregnant through a secret romance; the midwives get involved with a settlement of Irish Travellers.
Motherhood intertwines the lives of estranged friends in an unexpected way; Barbara and Sister Mary Cynthia aid an elderly man and his steadfast wife.
Trixie and Sister Mary Cynthia team up to support a deaf mother-to-be; Fred's daughter is less than delighted about his upcoming wedding.
As Tom and Shelagh scramble to prepare for a televised concert, a mother grapples with painful memories, and a sudden disappearance rocks Nonnatus.
The nuns' search grows desperate. Meanwhile, a measles outbreak threatens to derail the Christmas show, and Iris gets the surprise of her life.
The birth of a baby with severe deformities leaves a family and the midwives reeling. Trixie's new passion stirs up tensions with Sister Julienne.
The wife of a struggling dockworker begs Barbara for help with a dire situation. Sister Evangelina's war on formula has unexpected consequences.
The outbreak of a rare disease takes an emotional toll on Patsy, while a young teacher suffers painful repercussions for her unplanned pregnancy.
Sister Julienne makes a disturbing discovery in the hospital maternity ward, and an ambitious student suddenly finds his future in limbo.
A young mother's troubled past comes back to haunt her as she struggles to connect with her baby. Dr. Turner gets a wake-up call from his own son.
Shame allows an attacker to continue preying on women. Efforts to hide a teen's pregnancy take an alarming turn. Dr. Turner's family plans a surprise.
A proud transient woman resists medical and family assistance. A crisis helps distant newlyweds to bond. Sister Evangelina returns, but is changed.
Dr. Turner has a horrifying realization. Nonnatus House is dealt an unexpected blow. Swift action is taken to ensure a baby isn't born out of wedlock.
A call for help sends Nonnatus House staff to a mission hospital in rural South Africa, where Fred assists Nurse Crane with a birth in the wild.
Dr. Myra's condition worsens. A lack of water spurs Tom to visit a bitter landowner. Trixie makes a shocking discovery about Roza's long-awaited baby.
A sudden change in management rocks Nonnatus House. A young mother takes a brave stand against her abusive husband. Shelagh reveals a joyful surprise.
A couple with dwarfism ready for their baby's birth. An explosion at the docks reveals a woeful lack of preparedness. Patsy faces a painful duty.
Sister Ursula's new 20-minute limit on home visits has dire consequences for an out-of-sorts mother and newborn living in substandard housing.
Tom is deeply affected by the case of an expectant single mother with financial difficulties who reluctantly accepts an offer from a wealthy cousin.
While trying to find an appropriate home for a 21-year-old orphan with Down syndrome, Fred and Sister Monica Joan stumble upon an upsetting discovery.
Sister Mary Cynthia returns home, but her path to recovery won't be straightforward. A cultural practice complicates childbirth for a Somali woman.
A mother prescribed thalidomide during pregnancy asks Dr. Turner to help prepare her disabled toddler for the future. An accident stuns Nurse Crane.
Barbara and Tom must fast-track their plans. The day Shelagh has been waiting for finally arrives. Trixie sees the dark side of contraceptive pills.
As a historically harsh winter hits Poplar on Boxing Day 1962, Valerie is left shaken by a complicated delivery, while Barbara and Tom get big news.
New midwife Lucille Anderson arrives at Nonnatus House. Phyllis stands up to Sgt. Woolf so her terminally ill patient can die peacefully at home.
The Turners get an au pair. Lucille is blamed for a new mother's rare complication. An expectant father is pressured by his wife to attend the birth.
After a mother abandons her disheveled children at the clinic, Phyllis and Trixie visit their home to investigate. Magda shares a secret with Valerie.
A Pakistani husband returns from a trip to his homeland with a shocking surprise. Sister Monica Joan is diagnosed with cataracts but refuses surgery.
A sailor rumored to have smallpox is chased into hiding in Poplar. Lucille earns the trust of a traumatized expectant mother. Barbara and Tom return.
Barbara ministers to a newly arrived Irish family beset by multiple tragedies. Valerie and Lucille's health classes for teen girls anger one mother.
Barbara's condition is diagnosed but remains touch and go. Dr. Turner urges a teen husband in jail to turn his life around. Lucille tries a new church.
A separated mom-to-be moves in with her widowed dad, who's forced to tell a secret. The town comes together to celebrate Sister Monica Joan's birthday.
Three Chinese orphans and an election for a new mother superior bring Sisters Julienne and Winifred to the Mother House. A trend worries the midwives.
The nuns manage to talk to the woman lurking about the Mother House. After a spirited debate, the vote is held. Christmas cheer comes to the orphanage.
Two new nuns arrive at Nonnatus House. A feverish Sister Monica Joan disappears. The midwives must secretly help a model who had an illegal procedure.
Lucille helps an elderly woman with a hoarding problem. A Ghanaian patient's childbirth complications introduce Dr. Turner to an unfamiliar disease.
A measles vaccine trial attracts a mother who's overly anxious about her baby. A mom of five's confidence is shaken when her sixth is born "different."
An admirer takes Nurse Crane on a date. An ambitious mom gets an unwelcome surprise. A rift divides a mother and daughter, who are both pregnant.
Lucille catches a young man's eye. A bride-to-be reveals a worrying secret to Trixie, while a dad-to-be suffers odd symptoms during his wife's labor.
Mother Mildred fills in for an injured Phyllis. A dockworker receives an alarming diagnosis. Lucille helps a teen who's determined to keep her newborn.
Sister Frances attempts her first solo delivery. Gonorrhea forces a pregnant wife to face a painful truth. Valerie gets a shock from her grandmother.
Valerie finds herself in a difficult position. The Turners say goodbye to May. Sister Hilda helps to fulfill a terminally ill teenager's last wish.
Mother Mildred brings the Nonnatus House team to Scotland's Outer Hebrides to start a branch house and treat locals lacking access to medical care.
An emergency surgery forces Dr. Turner to face an old fear. Sister Monica Joan completes her spiritual quest. Reggie decides to set a world record.
When the circus comes to town, Nurse Crane realizes a dream. Shelagh coaches an old friend, who's had seven miscarriages, during her eighth attempt.
Nurse Crane discovers an outbreak of diphtheria in Poplar. Fred finds an abandoned baby in a dustbin. Sister Julienne receives troubling news.
Sister Julienne tries to help a pregnant prostitute. A woman becomes disoriented and forgets she's minding her granddaughter, leaving her unattended.
Lucille gets stuck in a lift with a racist woman in labor. A young immigrant mum is shunned by her husband. The midwives put on a charity fashion show.
Four young doctors arrive for a stay at Nonnatus House. Fred and Reggie befriend an ill man living in a condemned home who refuses to leave his pigeons.
A father-to-be's excessive worrying catches Sister Hilda's attention. Sister Monica Joan tries to finagle cinema tickets to "The Sound of Music."
The Turners' adoption of May is threatened by a visitor's arrival from overseas. A mum-to-be is determined to give birth on her late father's birthday.
Trixie helps prepare a blind mother to care for her newborn independently. Dr. McNulty's secret use of painkillers affects his professional judgment.
Sister Julienne gets an alarming letter. Valerie learns her grandmother is in hospital. Two pregnant women discover they share a shocking commonality.
Trixie begins a stint at a posh hospital. Dr. Turner links a newborn's complications to a father's past. A crisis of faith overwhelms Sister Monica Joan.
Trixie's recent patient Fiona is readmitted to Lady Emily's. A pregnant mother whose husband is away at sea wants to give up her next baby for adoption.
A clinic patient claims she's pregnant, but tests show otherwise. Shelagh proposes an idea that would increase Nonnatus House's funding.
The pupil midwives arrive. Dr. Turner treats a patient who is determined to "cure" his homosexuality. Trixie attends the christening of Fiona's baby.
A toddler's lack of development worries Sister Julienne. Tensions brew between a pregnant teen who wants to keep her baby and her controlling mother.
A Hindu woman's childbirth fears are traced to a childhood trauma. A desperate patient's actions compel Trixie to publicly speak out on an issue.
Horrified by a local tenement's living conditions, Sister Frances enlists Violet's help. A pregnant woman plans to grant her sister's wish to be a mum.
Past and present cast and crew members recall their favorite moments from the past 10 years and go behind the scenes to show how they were created.
As Christmas approaches, Cyril and Lucille prepare for their Boxing Day wedding and the midwives of Nonnatus House field several challenging cases.
A work crew's disturbing discovery in a Poplar building stirs up a family's secrets. One patient fears her second delivery will be like her first.
Lucille supports a single mother under scrutiny. Miss Higgins gets a terrible shock, and the midwives try to contain a scabies outbreak.
A talented young singer under Nurse Crane's care faces a difficult decision. Nancy connects with a homeless man who has fallen through the cracks.
A new father is haunted by his memories of the Holocaust. Cyril searches for a job and Trixie helps a young mother struggling to breastfeed her baby.
Trixie treats a man injured in a construction accident. Nancy and Sister Frances educate a primary school class. Nurse Crane gets big news.
Shelagh steps in to help cover cases while two midwives are away. Lucille grieves after a loss and Matthew encounters some free-spirited squatters.
Sister Frances befriends a lonely teenage mother and Sister Hilda challenges Nancy to reach her full potential. A disaster shocks all of Poplar.
After a devastating accident, everyone at Nonnatus House must pull together to help the community recover even while fearing for their own loved ones.
As they prepare for a holiday talent show, the midwives support an expectant mother released from prison and a family shaken by thalidomide's effects.
A new arrival from the Mother House bends a few rules and an inflammatory speech sows tensions in Poplar. Cancer brings a couple's secret to light.
Struggling herself, Lucille connects with an isolated patient. Trixie and Sister Julienne counsel a young woman facing a mysterious health problem.
Sister Veronica steps in when a new marriage becomes a nightmare. Nancy navigates a sticky situation. The Turners treat a baby with a rare condition.
Facing criticism, Nurse Crane defends her approach to midwifery. A contagious outbreak strikes the maternity home and Reggie battles puzzling malaise.
Matthew strives to show his father the true value of Poplar. Nancy asks for Cyril's help supporting a young man with a mental health crisis.
With wedding plans in full swing, Trixie mediates between a teen mother and her parents. Sister Veronica focuses on the district's youngest workers.
While a housing crisis impacts one of Nancy's pregnant patients, a mysterious outbreak of hepatitis cases strikes one of the Order's own.
As Trixie and Matthew's big day arrives, Shelagh advises a couple dealing with in-laws from different cultures, and Nancy weighs a momentous decision.
When Sister Monica Joan experiences holiday depression, her friends at Nonnatus House and in the community throw her a Christmas party to remember.
A new midwife trainee's first home birth unfolds during a police standoff. Dr. Turner assists an expectant mother who has cerebral palsy.
Nonnatus House nurses step in when council flat conditions sicken a pregnant mother and her daughter. A woman is diagnosed with a devastating illness.
When Fred falls dangerously ill, Violet pauses her mayoral campaign to be by his side. Nurse Crane helps a mother cope with her baby's hip dysplasia.
A tuberculosis case stirs up memories for Nancy. Trouble at home distracts Trixie at a crucial moment. Sister Monica Joan is over the moon for Apollo 11.
Violet arranges an eventful seaside outing. Nurse Crane and Dr. Turner help a young couple struggling with their children's unexpected diagnoses.
Cyril seeks the best resolution for a desperate mother forced to leave her two sons at the church. Trixie and Matthew suffer a reversal in fortune.
Trixie and Matthew look for a way out of their financial woes. Joyce and Rosalind confront new challenges as they officially join the Nonnatus team.
Surprise visitors reopen a chapter from Miss Higgins' past. Shelagh receives an ominous call. Poplar holds its annual Mother of the Year contest.