After helping take down Godzilla, biologist Dr. Nick Tatopoulos stumbles upon his hatchling, who bonds with the scientist as a parental figure. Recruiting his own environmentally-directed research outfit HEAT (Humanitarian Environmental Analysis Team) Nick sets out to study not only this new generation, but also to investigate the increasing reports of monsters of all types and other environmental anomalies menacing the Earth. Nicks team, accompanied by their 300-foot giant reptile, travel the globe defending humankind against mutant threats.