Caring for patients is a huge responsibility. Since the One Family One medical clinic was founded, the patients who go there have come to rely on the doctors to meet all of their physical and mental needs. Although he grew up as a rebellious, mischievous boy, Dr. Situ Li (Wong Hei) has taken over the practice from his father (Zhang Tong Zu), who founded the clinic, and now uses his humor to tease and joke with his patients. He works alongside Dr. Su Xi (Louisa So), who was one of his father’s best students and is much more serious about her work. As Situ Li and Su Xi try to work together, will they find that their approach to patient care is not that different after all?