Three years after a zombie apocalypse caused by a virus that killed most humans, Murphy (Keith Allan) is one of three inmates at Portsmouth Naval Prison in Kittery, Maine, unwilling participants in a government-approved experiment. Each inmate received a different test vaccine. Murphy was the only one to survive the vaccine injection.
He is therefore humanity's one and only hope. It is therefore imperative to keep him alive in order to produce other antidotes from his blood. Helped unwillingly by several companions including Garnett (Tom Everett Scott), a former member of the US National Guard, Warren (Kellita Smith), "Doc" (Russell Hodgkinson), "10 Thousand" (Nat Zang), "Addy" (Anastasia Baranova) and Mack (Michael Welch). They are guided by "Citizen Z" (DJ Qualls), who observes the world from his multiple computers.
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