Big Mouth

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Constance the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Andrew Rannells

Matthew MacDell (voice)

Ayo Edebiri

Missy Foreman-Greenwald (voice)

Jessica Chaffin

Shannon Glaser (voice)

Brandon Kyle Goodman

Walter the Lovebug (voice)

Pamela Adlon

Sonya the Lovebug (voice)

Joe Wengert

Caleb (voice) / Caleb / Dot #3 / Leore Paulblart (voice) / Caleb / Go-Gurt Burglar (voice) / Caleb / Go-Gurt Thief / Teacher (voice) / Caleb / IUD (voice) / Caleb / Lump Humpman (voice) / Caleb / Pornscape Residents (voice) / Caleb / Rewind Shirt Kid / Go

Richard Kind

Marty Glouberman (voice)

Paula Pell

(voice) / Barbara Glouberman (voice) / Barbara Glouberman / Bubbe (voice) / Barbara Glouberman / Lola's Couch Pillow (voice)

Neil Casey

(voice) / Detective Dumont (voice) / Detective Dumont / D.N. Ape (voice) / Detective Dumont / Lars (voice) / Lars (voice) / Lars / Boy (voice) / Lars / Detective Dumont (voice) / Lars / Detective Dumont / Pornscape Residents (voice) / Lars / Jew Penis (vo

Jak Knight

DeVon / DeVon (voice) / DeVon / Gina's Brother #2 (voice) / Tall Guy (voice)

June Diane Raphael

Devin (voice)

Jon Daly

Garrison Keillor / Magician #1 (voice) / Judd Birch (voice)

Seth Morris

(voice) / Greg Glaser (voice) / Ninth Grader (voice)

Kat Dennings

Leah Birch (voice) / Leah Birch / Lorraine the Hormone Monstress (voice)

Gina Rodriguez

Gina Alvarez (voice) / Gina Alvarez / Gina Parrot (voice)

Chelsea Peretti

Cellsea (voice) / Diaphragm (voice) / Monica Foreman-Greenwald (voice)

Heather Lawless

Jenna Bilzerian (voice)

Mark Rivers

(voice) / Backup Singer (voice) / Ghost of David Bowie (voice) / Man #2 / Penis Worms (voice) / Maury's Backup Singer (voice) / Michael Stipe Tampon (voice) / Siamese Twin #1 (voice) / Vendor (voice)

Gil Ozeri

(voice) / Brad (voice) / Jew Fishman (voice) / Man #1 / Dot #2 (voice) / The Ponytail Killer / Pornscape Residents (voice) / Wiggles (voice)

Mark Duplass

Val Bilzerian (voice)

David Thewlis

Shame Wizard (voice)

Nathan Fillion

Nathan Fillion (voice)

Zachary Quinto

Aiden (voice)

Emily Altman

(voice) / Milk (voice) / Olivia / Filmstrip Narrator (voice) / Vicky (voice)

Rob Huebel

Mr. Lizer (voice)

Paul Scheer

Kurt Bilzerian (voice)

John Gemberling

Security Guard / Bus Driver's Son (voice) / Tyler the Hormone Monster (voice) / Tyler the Hormone Monster / Dot #1 (voice)

Fran Gillespie

(voice) / Girl (voice) / Maddie the American Girl Doll / Choir Girl (voice) / Samira (voice)

Michaela Watkins

Cantor Dina Reznick (voice)

Ali Wong

Ali (voice)

Jean Smart

Depression Kitty (voice)

Maria Bamford

Tito the Anxiety Mosquito (voice)

Jack McBrayer

Pubic Hair #1 (voice)

Kristen Bell

Pam the Pillow (voice) / Uninterested Girl (voice)

Craig Robinson

(voice) / End Credits Singer (voice) / Pubic Hair #2 (voice)

Ashley London

(voice) / Kitty / DNA Expert / Pornscape Residents (voice) / Skank (voice) / The Virgin Mary / Waitress (voice)

Rosa Salazar

Ms. Benitez (voice)

Thandiwe Newton

Mona (voice)

Andy Daly

Dr. Wendy Engle (voice) / Dr. Wendy Engle / Motel Pillow #1 (voice) / Ghost of Harry Houdini (voice)

Bobby Cannavale

Gavin (voice) / Gavin the Hormone Monster (voice) / Nick's Agent (voice)

Natasha Lyonne

Suzette (voice)

Gary Cole

Andrew's Father (voice) / Edward MacDell (voice) / Matthew's Father (voice)

Julie White

Kimberly (voice) / Kimberly MacDell (voice)

Quinta Brunson

Girl (voice) / Quinta (voice)

John Oliver

Harry (voice)

Seth Rogen

Seth Goldberg (voice)

Kristen Wiig

Jessi's Vagina (voice)

Ayo Edebiri

Missy Foreman-Greenwald (voice) / Missy Foreman-Greenwald / Mosaic Missy (voice)

Brendan McCreary

Freddie Mercury (singing voice) / Ghost of Freddie Mercury (voice)

Zach Woods

Daniel (voice) / Sock (voice)

Ileen Goldsmith

(voice) / Jessi Glaser - singing double / Judd's Girlfriend (voice)

Carlos Alazraqui

Gustavo (voice)

Julie Klausner

Cherry Marashina (voice)

Chris Redd

(voice)

Josie Totah

Natalie (voice)

Lena Waithe

Lena (voice)

Sterling K. Brown

Michael Angelo (voice)

Joel Kim Booster

Charles Lu (voice)

Judd Hirsch

Lewis Glouberman (voice)

Chloe Fineman

Leah Birch (voice)

Patrick Page

Dread (voice)

Somali Rose

Missy’s Overalls

Jon Hamm

Scallops (voice)

Jon Gabrus

Movie Theater Customer (voice)

Anna Graves

Mrs. Albert (voice)

Nasim Pedrad

Fatima (voice)

Mae Whitman

Tallulah Levine (voice)

Chrissy Guerrero

Choir Girl (voice)

Philip Quinaz

Tanya Alvarez (voice)

Harvey Fierstein

Older Guy Town Resident (voice)

Jerry Minor

Man #3 / Singing Fish (voice)

Piotr Michael

Siamese Twin #2 (voice)

Marisa Lark Wallin

Reese's Wertherspoon / Woman (voice)

Crissy Guerrero

(voice)

Martin Short

Gordie (voice)

David Cross

Skip Glouberman (voice)

Carol Kane

Menopause Banshee / Old Woman (voice)

Tawny Newsome

(voice)

Retta

Duke's Mother (voice)

Wanda Sykes

Ghost of Harriet Tubman (voice)

Jaboukie Young-White

(voice)

Rob Riggle

Sgt. Adderall (voice)

Bobby Berk

Bobby Berk (voice)

Karamo Brown

Karamo Brown (voice)

Tan France

Tan France (voice)

Antoni Porowski

Antoni Porowski (voice)

Jonathan van Ness

Jonathan Van Ness (voice)

Anna Konkle

Izzy (voice)

Maya Erskine

Misha (voice)

Alia Shawkat

Roland (voice)

Paul Giamatti

Andrew’s Shit (voice)

Adam Scott

Mr. Keating (voice)

Hugh Jackman

himself (voice)

Kumail Nanjiani

himself (voice)

Keke Palmer

Rochelle the Hate Worm (voice)

Jemaine Clement

Simon Sex (voice)

Kristen Schaal

Bernie Sanders (voice)

Aidy Bryant

Emmy (voice)

Somali Rose

Missy’s Overalls