As the continuation of Zeta Gundam, this series once again follows the story of the Anti Earth Union Group (AEUG) battleship Argama after Zeta's final episode. To fight off the Axis Zeon, now called the Neo Zeon, Captain Bright Noa recruits a group of teenage junk collectors led by the loudmouthed but powerful Newtype Judau Ashta to pilot the Argama's mobile suits. Now sporting a line up of the behemoth MSZ-010 Double Zeta Gundam and the returning MSZ-006 Zeta Gundam, RX-178 Gundam Mk-II and Gundam-like MSN-00100 Hyaku Shiki, the group is nicknamed the Gundam Team. As such, this became the first of a number of Gundam series where a team of Gundam mobile suits fight alongside each other regularly. The climax takes place at Side 3 in the Battle of Axis.
Out of the major Zeta Gundam characters, only recurring captain Bright Noa and Axis leader Haman Karn make more than cameo appearances in ZZ; Char Aznable's planned appearance was canceled when Tomino was given the go-ahead to do the Mobile Suit Gundam: Char's Counterattack movie. Yoshiyuki Tomino's original plan for the show which involved Char's return was neither revealed though Glemy's sudden change in motivation seems to give a hint that he fills in for him at the end, nor does Tomino himself remember it and aside from the openings, Amuro Ray does not make an appearance in the series either. The alternate ending presented in Mobile Suit Zeta Gundam: A New Translation retcons the UC Gundam Universe, possibly eliminating the events of ZZ Gundam.